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Anterior Segment Grand Rounds

Case 1

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Chief complaint
Mr. GH (a 74-year-old male) was treated for conjunctivitis (OS) with Ocuflox. He reported back to the office 2 days later for follow-up. Some improvement was noted; however, he still complained of redness, foreign-body sensation, and tender left upper lid.

History
Past Ocular History: Chronic open angle glaucoma (COAG) S/P selective laser trabeculoplasty (SLT) for 2 weeks. Presently treated with Xalatan qhs OU. Past problems of nonresponsive or allergic reactions to other glaucoma medications. Questionable SLT response. Has trouble keeping IOP under control.
Past Medical History: Unremarkable. Recent history of lip herpes, no other facial lesions.

Exam

OD OS
Best corrected visual acuity: 20/25 20/30
External: trace injection 2+ diffuse injection with watery discharge
Pupils: PERRLA
Slit lamp: within normal limits cornea clear with no staining; anterior chamber clear; lid lesion (refer to videos below)
IOPs (applanation tonometry): 25mmHg 24mmHg

Left upper lid.

White light. [view video]

Fluorescein with cobalt filter. [view video]

Lissamine green. [view video]

Assessment
Herpes simplex blepharoconjunctivitis with ulcerative lid lesion (workup ruled out Herpes zoster). COAG--Not at goal; mild visual field defects OU.

Plan/Treatment (aggressive!)

  • Discontinued Ocuflox and Xalatan
  • Began 1% Viroptic solution q2h x 5 days
  • Began 500 mg Valtrex po tid x 7 days

1-week follow-up

  • Resolved lesion
  • IOPs (applanation tonometry): OD 31mmHg, OS 29mmHg
  • Began monocular trial of 0.5% Betimol q am--rule out contraindications to beta blockers

2-month follow-up: OD 21mmHg, OS 21mmHg. At goal?


What caused the Herpes simplex flare-up in this patient? Read more about

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URL: http://www.opt.indiana.edu/ce/antseg/case1.htm
Revised: November 20, 2004
IU Optometry home page: http://www.opt.indiana.edu/
Comments (content): Dr. Vic Malinovsky at malinovs@indiana.edu
Comments: Web Administrator
Page design and coding: Terri Greene
Copyright © 2004, The Trustees of Indiana University