Systemic evaluation revealed previously undetected lung carcinomas with multiple lymph node involvement and brain metastases.

Uveal metastatic lesions are the most common intraocular tumor. The number one primary site in women is the breast; in men it is the lung. Choroid around 90 percent, ciliary body about 8 percent, and iris 1-2 percent. Up to 7 percent of carcinoma patients get uveal metastases. The primary site is often never determined. The average survival rate is less than one year from the time of diagnosis. Metastatic choroidal tumors differ in appearance from primary choroidal lesions. They tend to be located in the posterior pole due to blood supply. They can be bilateral or unilateral (unilateral 3 to 1). Breast metastases are most likely to be bilateral. Single lesion or multiple lesions can occur. RPE detachments may occur. Uveal metastases are creamy yellow in color (may have orange hue), oval to placoid, and relatively flat (rarely break through Bruch's membrane). They produce high internal reflectivity on ultrasound.

Below are examples of metastatic choroidal tumors from other patients. (Some photos courtesy of Dr. Vic Malinovsky, IU School of Optometry)
Metastatic Carcinoma (lung)
B-scan of lesion (note elevation and internal reflectivity)
Primary choroidal melanoma		B-scan of the same melanoma
After treatment with radiation retinopathy
B-scan: choroidal nevus
Primary Choroidal Melanoma
Retinoblastoma

Treatment options include photocoagulation, radiation, chemotherapy, enucleation. Radioactive plaques are not practical for multiple foci.