Coat's Disease is an idiopathic retinal condition consisting of telangiectatic and aneurysmal vessels with significant exudation. There are two forms: common adolescent form and less common adult form. There is a 3 times greater occurrence in males than females; 80% unilateral. Children often present with leukocoria, poor vision, and strabismus. Adult onset cases frequently associated with elevated serum cholesterol.

Clinical picture is extremely variable. May or may not be able to distinguish vessel abnormalities ophthalmoscopically. Exudation may be mild or massive.

IVFA most helpful tool in making diagnosis.

The disease tends to be progressive but can have exacerbations and quiet periods. Photocoagulation is the treatment of choice.