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Generic name: |
brinzolamide |
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Concentration: |
1% |
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Mechanism of action: |
This carbonic anhydrase inhibitor reduces the aqueous humor production, thus lowering the pressure in the eye. |
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Indications: |
Treatment of open angle glaucoma or ocular hypertension. |
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Dosage: |
Instill one drop of brinzolamide ophthalmic solution into the affected eye(s) three times daily, 8 hours apart. |
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Use with caution in patients with/during: |
- Renal impairment or severe renal disease (with a creatinine clearance less than 30 milliliters per minute).
- Hepatic disease.
- Sulfonamide hypersensitivity.
- Acute closed angle glaucoma.
- Pregnancy, breast feeding or in children.
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Side effects: |
Common
- Blurred vision
- Bitter, sour, or unusual taste
Life-Threatening Symptoms
- Chest pain
- Jaundice (yellowing of skin or eyes)
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Less Common to Rare
- Dermatitis
- Chest pain
- Conjunctivitis (inflammation of the conjunctiva)
- Diarrhea
- Dizziness
- Double vision
- Dry eye
- Dry mouth
- Keratoconjunctivitis
- Dyspepsia (upset stomach)
- Eye discomfort or pain
- Blepharitis (inflammation of the eyelids)
- Keratitis (corneal inflammation)
- Tearing
- Hyperemia (increased amount of blood in eye)
- Headache
- Foreign body sensation in eye
- Dyspnea (shortness of breath)
- Rhinitis
- Keratopathy
- Ocular itching
- Ocular discharge
- Nausea
- Alopecia (hair loss)
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Notes: |
Brinzolamide is a sulfonamide and may cause a severe allergic reaction in patients with a sulfa drug allergy. |
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