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Angle on Glaucoma: Medications
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Iopidine ®

Generic name: apraclonidine hydrochloride
Concentration: 0.5%, 1.0%
Mechanism of action: This selective alpha-2 adrenergic agonist reduces the aqueous humor production and thus decreases intraocular pressures.
Indications: Treatment of open angle glaucoma or ocular hypertension.
Dosage: Instill one to two drop of apraclonidine ophthalmic solution into the affected eye(s) three times daily, 8 hours apart. Consult your doctor for dosing.
Use with caution in patients with/during:
  1. Severe cardiac disease, cerebrovascular disease, or coronary artery disease.
  2. Renal impairment or damage or hepatic disease.
  3. Pregnancy, breast feeding or in children.
Side effects:
Common
  • Tearing
  • Eye discomfort
  • Red eyes
  • Foreign body sensation in eye
  • Eyelid swelling
  • Dry mouth
  • Burning and itching eyes
  • Blurred vision

Less Common to Rare
  • Allergic reaction
  • Mydriasis (dilated pupils)

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URL: http://www.opt.indiana.edu/clinics/pteduc/glaucoma/meds/iopidine.htm
Revised: March 19, 2002
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Page design and coding: Terri Greene
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