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Angle on Glaucoma: Medications
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Optipranolol ®

Generic name: metipranololetaxolol hydrochloride
Concentration: 0.3%
Mechanism of action: This beta blocker reduces the aqueous humor production, increases drainage, and alters the blood flow of the eye--thus lowering the pressure.
Indications: Treatment of open angle glaucoma and ocular hypertension.
Dosage: Instill 1 drop of the solution into eye every 12 hours or twice a day.
Use with caution in patients with/during:
  1. Metipranolol should NOT be used in patients with preexisting cardiac disease, such as severe bradycardia, advanced AV block, cardiogenic shock, coronary artery disease, vasospastic angina, or congestive heart failure, particularly those with severe left ventricular dysfunction.
  2. Asthma or pulmonary disease (COPD, emphysema, bronchitis).
  3. Diabetes mellitis because it can mask symptoms of hypoglycemia.
  4. Hyperthyroidism because it may mask tachycardia.
  5. Using an oral beta blocker
  6. Kidney or liver impairments.
  7. Raynaud's disease or peripheral vascular disease.
  8. Myasthenia gravis.
  9. Psoriasis.
  10. Pregnancy, breast feeding or in children.
Side effects:
Common
  • Stinging or irritation of eye when medicine applied
  • Redness of eye or inside of eyelid
  • Decreased night vision
  • Blurred vision

Life Threatening Symptoms

  • None expected

Less Common to Rare
  • Increased sensitivity to light
  • Dryness, inflammation, discharge or pain in eye
  • Crusty eyelids
  • Changes in vision
  • Headache
  • Chest pain
  • Rapid or slow heart beat
  • Sensation of foreign body in eye

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URL: http://www.opt.indiana.edu/clinics/pteduc/glaucoma/meds/optipran.htm
Revised: March 19, 2002
IU Optometry home page: http://www.opt.indiana.edu/
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Page design and coding: Terri Greene
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