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Generic name: |
dorzolamide hydrochloride |
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Concentration: |
2% |
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Mechanism of action: |
This carbonic anhydrase inhibitor reduces the aqueous humor production, thus lowering the pressure in the eye. |
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Indications: |
Treatment of open angle glaucoma or ocular hypertension. |
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Dosage: |
Instill one drop of dorzolamide ophthalmic solution into the affected eye(s) three times daily, 8 hours apart. |
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Use with caution in patients with/during: |
- Renal impairment or severe renal disease (with a creatinine clearance less than 30 milliliters per minute).
- Hepatic disease.
- Sulfonamide hypersensitivity.
- Acute closed angle glaucoma.
- Pregnancy, breast feeding or in children.
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Side effects: |
Common
- Allergic eye reaction (eye itchiness redness or swelling)
- Bitter taste
- Stinging or burning on application
- Sensation of something in the eye
- Light sensitivity
Life-Threatening Symptoms
- Allergic reactions in patients who are also allergic to sulfonamides
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Less Common to Rare
- Unusual fatigue
- Blurred vision
- Dry eyes
- Tearing
- Nausea
- Skin rash
- Headache
- Urolithiasis (blood in the urine), nausea, vomiting, back or side pain
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Notes: |
Dorzolamide is a sulfonamide and has may cause a severe allergic reaction in patients with a sulfa drug allergy. |
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